2005 US Frontiers of Science Symposium

2005 US Frontiers of Science Symposium

The Silent Revolution: A Brief Introduction to MicroRNAs and Small Interfering RNAs

Frank Slack, Yale University

1. The Silent Revolution: A brief introduction to microRNAs and small interfering RNAs

2. The Central Dogma

3. Many Types of RNA in cells

4. MicroRNAs were discovered by Victor Ambros and Gary Ruvkun in C. elegans

5. Many Types of RNA in cells

6. MicroRNAs were discovered by Victor Ambros and Gary Ruvkun in C. elegans

7. let-7 and lin-4 are the founding microRNAs

8. How many miRNAs?

9. The function of ~20 animal miRNAs are known

10. Animal miRNAs regulate vertebrate development

11. MicroRNAs are related to small interfering RNAs involved in RNA interference

12. Animal miRNAs regulate vertebrate development

13. The function of ~20 animal miRNAs are known

14. Animal miRNAs regulate vertebrate development

15. MicroRNAs are related to small interfering RNAs involved in RNA interference

16. RNAi was discovered by Andy Fire and Craig Mello in C. elegans

17. The growing world of small regulatory RNAs

18. Fundamental questions in miRNA biology

19. Greg Hannon: Applications of miRNAs/siRNAs

20. Current Members of the Slack lab

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Copyright © 2005. National Academy of Sciences. All rights reserved.